Progesterone (P)

Progesterone wani muhimmin progestogen ne, wanda ke cikin hormones na steroid, tare da nauyin kwayoyin halitta na 314.5.Ana samar da shi ne ta hanyar corpus luteum na ovary da kuma mahaifa a lokacin daukar ciki.Shi ne farkon testosterone, estrogen da adrenal cortex hormones.Matsayin progesterone da aka samar a lokacin follicular lokaci na maza da mata na al'ada yana da ƙasa sosai, bayan yawo cikin jini, an ɗaure shi da albumin da furotin na jima'i da ke ɗaure furotin kuma yana yawo a cikin jiki.

Babban aikin progesterone shine sanya mahaifa ta shirya don dasa ƙwai da aka haɗe da kuma kula da ciki.A lokacin follicular lokaci na sake zagayowar haila, matakin progesterone ya ragu.Bayan kwai, progesterone da corpus luteum ya samar yana ƙaruwa da sauri, kuma ya kai matsakaicin matsakaicin 10ng/mL-20ng/mL a cikin kwanaki 5-7 bayan ovulation.Idan ba a yi ciki ba, corpus luteum atrophies a cikin kwanaki huɗu na ƙarshe na sake zagayowar haila kuma ƙwayar progesterone yana raguwa zuwa lokaci na follicular.Idan an yi ciki, corpus luteum ba ya ɓacewa kuma ya ci gaba da ɓoye progesterone, yana ajiye shi a matakan daidai da matsakaicin lokaci na luteal kuma ya ci gaba har zuwa mako na shida na ciki.A lokacin daukar ciki, mahaifa a hankali ya zama babban tushen progesterone, kuma maida hankali yana ƙaruwa daga 10ng/ml-50ng/mL a farkon watanni 3 na ciki zuwa 50ng/ml-280ng/ml a cikin watanni 7-9.Nazarin asibiti ya nuna cewa progesterone yana taka rawa wajen inganta kwai da kuma kula da aikin al'ada na corpus luteum a cikin mata marasa ciki.Idan progesterone da corpus luteum ya samar bai isa ba, yana iya nuna cewa aikin corpus luteum bai isa ba, kuma rashin isasshen aikin corpus luteum yana da alaƙa da rashin haihuwa da farkon zubar da ciki.