Staphylococcus Aureus da Methicillin-Resistant Staphylococcus Aureus Nucleic Acid

Staphylococcus aureus yana daya daga cikin mahimman kwayoyin cuta na kamuwa da cuta na nosocomial.Staphylococcus aureus (SA) na cikin staphylococcus ne kuma wakili ne na kwayoyin cutar Gram-positive, wanda zai iya samar da nau'i na gubobi da enzymes masu lalata.Kwayoyin cuta suna da halaye na rarrabawa mai yawa, ƙaƙƙarfan pathogenicity da babban juriya.Halin da ake iya ɗauka na nuclease (nuc) wani ƙwayar cuta ce ta staphylococcus aureus.A cikin 'yan shekarun nan, saboda yawan amfani da kwayoyin hormones da shirye-shiryen rigakafi da kuma cin zarafin maganin rigakafi masu yawa, cututtuka na nosocomial da ke haifar da Staphylococcus aureus na Methicillin (MRSA) a cikin Staphylococcus sun kasance suna karuwa.Matsakaicin adadin gano MRSA na ƙasa ya kasance 30.2% a cikin 2019 a China.An raba MRSA zuwa MRSA mai alaƙa da kiwon lafiya (HA-MRSA), MRSA mai alaƙa da al'umma (CA-MRSA), da MRSA mai alaƙa da dabbobi (LA-MRSA).CA-MRSA, HA-MRSA, LA-MRSA suna da babban bambance-bambance a cikin ƙwayoyin cuta, juriya na ƙwayoyin cuta (misali, HA-MRSA yana nuna juriya fiye da CA-MRSA) da halaye na asibiti (misali wurin kamuwa da cuta).Bisa ga waɗannan halaye, CA-MRSA da HA-MRSA za a iya bambanta.Koyaya, bambance-bambancen da ke tsakanin CA-MRSA da HA-MRSA suna raguwa saboda yawan motsin mutane tsakanin asibitoci da al'ummomi.MRSA yana da juriya da magunguna da yawa, ba wai kawai juriya ga maganin rigakafi na β-lactam ba, har ma da aminoglycosides, macrolides, tetracyclines da quinolones zuwa digiri daban-daban.Akwai manyan bambance-bambancen yanki a cikin ƙimar juriya na ƙwayoyi da halaye daban-daban.

Halin metcillin juriya na mecA yana taka muhimmiyar rawa a juriya na staphylococcal.Ana ɗaukar kwayar halittar akan wani nau'in kwayoyin halitta na wayar hannu na musamman (SCCmec), wanda ke ɓoye furotin mai ɗaure penicillin 2a (PBP2a) kuma yana da ƙarancin kusanci ga maganin rigakafi na β-lactam, ta yadda magungunan ƙwayoyin cuta ba za su iya hana haɗin bangon peptidoglycan Layer ba. haifar da juriya na miyagun ƙwayoyi.