Enterococcus da Vancomycin mai jurewa da kwayoyin halitta

Juriya ga Drug kuma an san shi da juriya na miyagun ƙwayoyi, yana nufin juriya na ƙwayoyin cuta zuwa aikin magungunan ƙwayoyin cuta.Da zarar juriya na miyagun ƙwayoyi ya faru, tasirin chemotherapy na kwayoyi zai ragu sosai.Juriya ga Drug ya kasu zuwa juriya na ciki da juriya da aka samu.Juriya na ciki yana ƙayyade ta kwayoyin chromosomal na kwayan cuta, sun wuce daga tsara zuwa tsara, kuma ba zai canza ba.Juriya da aka samu shine saboda gaskiyar cewa bayan haɗuwa da maganin rigakafi, ƙwayoyin cuta suna canza hanyoyin rayuwa ta yadda ba a kashe su ta hanyar maganin rigakafi.

Kwayoyin juriya na vancomycin VanA da VanB sun sami juriya na ƙwayoyi, daga cikinsu VanA yana nuna yawan juriya ga vancomycin da teicoplanin, VanB yana nuna matakan juriya ga vancomycin daban-daban, kuma yana kula da teicoplanin.Ana amfani da Vancomycin sau da yawa a asibiti don magance cututtukan ƙwayoyin cuta na Gram-positive, amma saboda bullowar cutar sankarau (VRE), musamman enterococcus faecalis da enterococcus faecium, wanda ya kai fiye da 90%, ya haifar da sabbin ƙalubale ga magungunan asibiti. .A halin yanzu, babu takamaiman maganin rigakafi don maganin VRE.Menene ƙari, VRE kuma na iya watsa kwayoyin juriya na miyagun ƙwayoyi zuwa sauran enterococci ko wasu ƙwayoyin cuta na Gram.