KRAS 8 maye gurbi

Takaitaccen Bayani:

Wannan kit ɗin an yi niyya ne don gano ingancin in vitro na maye gurbi guda 8 a cikin codons 12 da 13 na K-ras gene a cikin DNA da aka ciro daga sassan cututtukan cututtukan ƙwayar cuta na ɗan adam.


Cikakken Bayani

Tags samfurin

Sunan samfur

HWTS-TM014-KRAS 8 Kayan Gane Maɓalli (Fluorescence PCR)

HWTS-TM011-Daskare-bushewar KRAS 8 Kit ɗin Gane Maɓalli(Fluorescence PCR)

Takaddun shaida

CE

Epidemiology

An gano maye gurbi a cikin kwayar halittar KRAS a cikin nau'ikan nau'ikan ƙwayar cuta na ɗan adam, kusan 17% ~ 25% maye gurbi a cikin ƙari, 15% ~ 30% maye gurbi a cikin marasa lafiya na huhu, 20% ~ 50% maye gurbi a cikin ciwon daji mai launi. marasa lafiya.Saboda furotin na P21 da K-ras gene ke ƙullawa yana ƙarƙashin hanyar siginar EGFR, bayan maye gurbi na K-ras, hanyar siginar siginar koyaushe ana kunna ta kuma magungunan da aka yi niyya na sama ba su shafar su akan EGFR, wanda ke haifar da ci gaba. m yaduwa na sel.Maye gurbi a cikin kwayar halittar K-ras gabaɗaya yana ba da juriya ga masu hana EGFR tyrosine kinase a cikin masu cutar kansar huhu da juriya ga magungunan rigakafin EGFR a cikin masu cutar kansar launi.A cikin 2008, National Comprehensive Cancer Network (NCCN) ta ba da ƙa'idar aikin asibiti don ciwon daji na colorectal, wanda ya nuna cewa wuraren maye gurbi da ke haifar da kunna K-ras galibi suna cikin codons 12 da 13 na exon 2, kuma sun ba da shawarar cewa. za a iya gwada duk marasa lafiya da ke da ci-gaban ciwon daji na launin fata don maye gurbin K-ras kafin magani.Don haka, saurin gano ainihin ƙwayoyin halittar K-ras yana da mahimmanci a cikin jagorar magunguna na asibiti.Wannan kit ɗin yana amfani da DNA a matsayin samfurin ganowa don samar da ƙima na ƙima na matsayin maye gurbi, wanda zai iya taimakawa likitocin a tantance cutar kansar launin fata, ciwon huhu da sauran masu ciwon daji waɗanda ke amfana da magungunan da aka yi niyya.Sakamakon gwajin kit ɗin don nunin asibiti ne kawai kuma bai kamata a yi amfani da shi a matsayin kawai tushen jiyya na daidaikun marasa lafiya ba.Ya kamata ma'aikatan asibiti su yi cikakkun hukunce-hukunce kan sakamakon gwajin bisa dalilai kamar yanayin majiyyaci, alamun magunguna, amsawar jiyya da sauran alamun gwajin gwaji.

Ma'aunin Fasaha

Adana Liquid: ≤-18 ℃ A cikin duhu;Lyophilized: ≤30 ℃ A cikin duhu
Rayuwar rayuwa Ruwa: watanni 9;Lyophilized: watanni 12
Nau'in Samfura Nama ko sashe da ke tattare da paraffin ya ƙunshi ƙwayoyin cuta
CV ≤5.0%
LoD K-ras Reaction Buffer A da K-ras Reaction Buffer B na iya gano ƙimar maye gurbin 1% a ƙarƙashin nau'in nau'in daji na 3ng/μL
Abubuwan da ake Aiwatar da su Abubuwan da aka Aiwatar da Biosystems 7500 Tsarin PCR na Gaskiya

Abubuwan da aka Aiwatar da Biosystems 7300 Tsarin PCR na Gaskiya

QuantStudio®5 Tsarin PCR na Gaskiya

LightCycler® 480 Tsarin PCR na Gaskiya

BioRad CFX96 Tsarin PCR na Gaskiya

Gudun Aiki

Ana ba da shawarar yin amfani da Kit ɗin Tissue na QIAGEN na QIAamp DNA FFPE (56404) da na'urar cirewar Tissue DNA Rapid Extraction Kit (DP330) wanda Tiangen Biotech(Beijing) Co., Ltd ke ƙera.


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